Ibuprofen side effects: A sign on the knuckles that indicates kidney problems

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Swollen ankles after taking ibuprofen may mean you have developed a kidney problem. Blood in the urine or no urine “at all” can also indicate kidney problems.

Kidney problems associated with ibuprofen include chronic kidney disease (CKD). CKD is a long-term condition in which the kidneys “don't work as well as they should.”

CKD can get worse over time, and eventually the kidneys may stop working altogether, but this is rare. Many people with CKD can live a long life with this disease.

Other symptoms of CKD include fatigue, shortness of breath, and feeling unwell. Chronic kidney disease is “usually” caused by other conditions that put stress on the kidneys.

These may include:

• High blood pressure – this can cause strain on the small blood vessels in the kidneys and stop the kidneys from working normally.
• Diabetes – too much glucose in the blood can damage the tiny filters in the kidneys.
• High cholesterol is can cause fatty deposits to build up in the blood vessels that supply the kidneys, which can make it difficult for them to work properly.
• Kidney infections.
• Glomerulonephritis – inflammation of the kidneys.
• Long-term , regular use of certain medications such as lithium and nonsteroidal anti-inflammatory drugs.

About one in 100 people experience the “common” side effects of taking ibuprofen.

This includes:

• Headaches
• Feeling dizzy
• Feeling sick (nausea)
• Sickness (vomiting)
• Indigestion

If these side effects become unmanageable, you should seek medical help.