Scientists have proposed a new way to improve the effectiveness of chemotherapy
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The use of low-intensity pulsed ultrasound in combination with microbubbles can improve delivery of chemotherapy drugs used to treat cancer.
In their study, a group of Lithuanian researchers from three universities reported that the survival time of microbubbles is the best indicator for determining the effectiveness of sonoporation, that is, the rupture of the cancer cell membrane caused by ultrasound.< /p>
Today, a method in which ultrasound together with microbubbles is used to improve the delivery of anticancer drugs to affected cells is widely researched.
Although research is mainly conducted in laboratory conditions in vitro, the first clinical trials have already started. A new class of anticancer drugs may be effective in treating common types of leukemia.
“Our main conclusion is that only the estimation of the survival time of microbubbles is needed to predict the effectiveness of sonoporation. Therefore, our indicators are more advanced than the currently used inertial cavitation control variable,” the authors of the study explain.
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